NeuroMab™ Anti-OPN BBB Shuttle Antibody(NRZP-1022-ZP2613)
- Host Species:
- Chimeric; Humanized
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; Inhihb; ELISA; In Vitro; In Vivo
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Lot Number
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Clonality
Host Species
Applications
Relevant Diseases
Storage
Research Use Only
Target
Official Name
Full Name
Alternative Names
Bone sialoprotein 1;
Bone sialoprotein I;
BSP I;
BSPI;
Early T lymphocyte activation 1;
ETA 1;
ETA1;
MGC110940;
Nephropontin;
OPN;
Osteopontin;
Fig.1 shows the result of measuring the affinity of the OPN small peptide and the anti-OPN chimeric antibody.
EC50 values were calculated from the 4-parameter fit equation using Prism Graphpad using the data from FIG.10. A2=2.6 ng/mL, A6=3.2 ng/mL; E5=4.0 ng/mL and G7=93.2 ng/mL.
Fig.2 shows the results of measuring the affinity of the anti-OPN chimeric antibody.
EC50 values were calculated from the 4-parameter fit equation using Prism Graphpad using the data from FIG.10. A2=2.6 ng/mL, A6=3.2 ng/mL; E5=4.0 ng/mL and G7=93.2 ng/mL.
Fig.3 shows the results of inhibiting the proliferation of non-small cell lung cancer cell A549 by the anti-OPN chimeric antibody (antibody 72B) in example 6 for 48 hours.
EC50 values were calculated from the 4-parameter fit equation using Prism Graphpad using the data from FIG.10. A2=2.6 ng/mL, A6=3.2 ng/mL; E5=4.0 ng/mL and G7=93.2 ng/mL.
Fig.4 is a tumor growth curve.
EC50 values were calculated from the 4-parameter fit equation using Prism Graphpad using the data from FIG.10. A2=2.6 ng/mL, A6=3.2 ng/mL; E5=4.0 ng/mL and G7=93.2 ng/mL.
Fig.5 shows the result of measuring the affinity of the OPN small peptide and the anti-OPN chimeric antibody.
EC50 values were calculated from the 4-parameter fit equation using Prism Graphpad using the data from FIG.10. A2=2.6 ng/mL, A6=3.2 ng/mL; E5=4.0 ng/mL and G7=93.2 ng/mL.
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