Mouse Anti-ubiquilin 2 Monoclonal Antibody (CBP6691)
[CAT#: NAB2007FY1552]
Mouse Monoclonal to ubiquilin 2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat; Mouse
- Applications:
- WB; IF; IHC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
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Description
Ubiquitin 2, also known as PLIC2 and Chap1, is one of the four members of the ubiquitin protein family, which can regulate cellular protein degradation through proteasome or autophagy-like pathways (1-3). All ubiquitins contain an N-terminal ubiquitin-like (UBL) domain and a C-terminal ubiquitin-associated (UBA) domain, and the central part of the molecule is highly variable. The UBL domain binds to the subunits of the proteasome, while the UBA domain binds to the polyubiquitin chain, which usually binds to a protein labeled for proteasome degradation. Mutations in the ubiquitin 2 gene that cause protein point mutations are associated with certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTLD) (4).
Immunogen
Human Ubiquitin 2 expressed and purified in E. coli
Species Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP6691
Applications
WB; IF; IHC
Application Notes
WB: 1:1000-1:2000
IF/ICC and IHC: 1:1000
IF/ICC and IHC: 1:1000
Product Properties
Form
Liquid
Formulation
50% PBS, 50% glycerol
Preservatives
5mM NaN3
Concentration
1 mg/ml
Shipping
Gel Pack
Storage
Store at 4°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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