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Creative Biolabs

Mouse Anti-NEFM Monoclonal Antibody (CBP6780)

[CAT#: NAB2007FY1729]

Neurons

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IHC; WB

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Product Overview

Description

Neuroinflammation broadly defines the collective response Immune response in the brain and spinal cord Injuries and illnesses. Central nervous system inflammation (CNS) Usually related to different levels of organization Damage, such as loss of myelin sheath and neurons. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Epitope

Binds to an located within the peptide sequence SDHLEEDIHRLKERF

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP6780

Applications

IHC; WB

Application Notes

IHC: 1:5000-1:10000
WB: 1 µg/ml

Research Areas

Neuron
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, 40% glycerol

Preservatives

0.02% Sodium azide

Concentration

1 mg/ml

Purification

Protein A purified

Shipping

Gel Pack

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

NEFM

Official Name

NEFM

Full Name

Neurofilament Medium

Alternative Names

Neurofilament Medium; Neurofilament, Medium Polypeptide 150kDa; Neurofilament Triplet M Protein; 160 KDa Neurofilament Protein; Neurofilament 3; NEF3

Gene ID

4741(Human); 18040(Mouse); 24588(Rat)

Uniprot ID

P07197(Human); P08553(Mouse); P12839(Rat)
Publications

Publications (0)

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