Product
Human CHO-K1/D2s/Gα15 Stable Cell Line
[CAT#: NCL20120056CR]
D2 (Short) Dopamine Receptor Stable Cell Line
- Species:
- Human
- Applications:
- GPCR Screening
- Cell Types:
- CHO-K1; GPCR Cell
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
The D2 dopamine receptor, short form (D2s) has been shown to stimulate phospholipase D (PLD) activity independent of the activation of phospholipase C (PLC) activity in GH4 derived cells stably transfected with the D2s receptor. Agonist activation of D2s has been shown to mediate the inhibition of growth in the same cell line.
Cell Types
CHO-K1; GPCR Cell
Applications
GPCR Screening
Research Areas
GPCR; Neural Signal Transduction
Species
Human
Properties
Size
>1x10^6 Cells
Form
Frozen cells
Culture Medium
Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, 200 μg/ml Zeocin
Freeze Medium
45% culture medium, 45% FBS, 10% DMSO
Receptor
D2(Short)
Family
Dopamine receptor
Strain
D2s/Gα15 Cell Line
Cell Purity
>95%
Shipping
Dry ice
Storage
Liquid nitrogen immediately upon delivery
Handling Advice
Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
repeated exposure.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Warnings
Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details
Target
D2
Official Name
D2
Alternative Names
D2 receptor; D2A and D2B; D2(415) and D2(444); dopamine D2 receptor; D(2) dopamine receptor; dopamine receptor 2; dopamine receptor D2; Drd-2; D2 receptor; D2R
References
1. Watanabe, H., Matsushita, N., Shimizu, Y., Iikuni, S., Nakamoto, Y., Togashi, K., & Ono, M. (2019). Synthesis and characterization of a novel 18 F-labeled 2, 5-diarylnicotinamide derivative targeting orexin 2 receptor. MedChemComm, 10(12), 2126-2130.
Publications
Publications (0)
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
