Product

Human CHO-K1/VPAC2/Gα15 Stable Cell Line

[CAT#: NCL20120138CR]

VPAC2 Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: CHO-K1; GPCR Cell

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Product Overview

Description

It is a Gs-coupled receptor expressed in the stroma of uterus and prostate; smooth muscles in gastrointestinal tract, seminal vesicles and skin; blood vessels; thymus. VPAC2 is an essential regulator of the circadian pacemaker of the hypothalamic suprachiasmatic nuclei.

Cell Types

CHO-K1; GPCR Cell

Applications

GPCR Screening

Research Areas

GPCR; Neural Stem Cell

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, 200 μg/ml Zeocin

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

VPAC2

Family

VIP and PACAP receptor

Strain

VPAC2/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

VPAC2

Official Name

VIPR2

Alternative Names

VIP2; PACAP-3; PVR3; VIP2/PACAP; VIP2; PACAP3; PVR2; VPAC2; VPAC2R; VIP and PACAP receptor 2; PACAP-R-3; PACAP-R3; PACAP type III receptor; VIP-R-2; pituitary adenylate cyclase-activating polypeptide type III receptor; vasoactive intestinal peptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP receptor subtype 2

Gene ID

7434(Human); 22355(Mouse); 29555(Rat)

Uniprot ID

P41587(Human); P41588(Mouse); P35000(Rat)

References

1. Mi, G., Liu, S., Zhang, J., Liang, H., Gao, Y., Li, N.,.. & Yang, Z. (2017). Levo-tetrahydroberberrubine produces anxiolytic-like effects in mice through the 5-HT 1A receptor. PloS one, 12(1), e0168964.

Publications