Human Trabecular Meshwork Cells, Adult

[CAT#: NCL-2103-P31]

Positive for Fibronectin

Species:: Human

Cell Types:: Visual system-related Cells

Cell Subtypes:: Trabecular Meshwork Cells

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Product Overview

Description

Human trabecular meshwork cells (HTMC) are endothelial-like cells in the spongy connective tissue located in the front of the eye.htmC forms a layer of light beam, which is part of the fibrous basement membrane that contains the extracellular matrix and cells. In areas of high resistance to outflow.htmC regulates intraocular pressure by controlling the drainage of fluid into the tube that flows into the blood. Changes i.htmC contractility and tension mediate outflow. Due to its phagocytosis.htmC can also be used as a self-cleaning filter. Live cell imaging of the cytoskeleton provides valuable information for actin dynamics i.htmC. Other research aims to identify treatments that rela.htmC contractions to increase fluid outflow and reduce intraocular pressure. The specific targeting effect o.htmC can also play a clinical role by increasing the therapeutic efficacy of nanoparticles for gene delivery.

Cell Types

Visual system-related Cells

Cell Subtypes

Trabecular Meshwork Cells

Species

Human

Properties

Tissue Source

Normal healthy human adult eyes

Cell Purity

>95%

Cell Viability

>90%

Mycoplasma Testing

The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.

Sterility Testing

Sterility testing was performed in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Genetic Stability Testing

Cell genetic stability study was perfomed under ICH guidelines. We provide guidance on the appropriate testing program upon your requirements.

Shipping

Dry ice

Storage

Liquid Nitrogen

Handling Advice

Frozen cells: Upon receipt, frozen ampoules should be transferred directly to gaseous phase liquid nitrogen without delay, unless they are to be used straight away.

Growing cells: Growing cell cultures should be checked on receipt using an inverted microscope. Immediately check the cell density upon arrival for any obvious defects. If the cell density is too high (more than 80% confluent) subculture the cells (harvest and reseed) immediately.

For detailed instructions on the thawing procedure of frozen cells and the culture of adherent or suspended cells, please feel free to contact us by email or phone.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents. It is recommended to use cells within ten generations.