Mouse Olfactory Bulb Cells (Obc13), Immortalized

[CAT#: NCL-2108P120]

Species:: Mouse

Applications:: Cell Culture

Cell Types:: Olfactory system-related Cells

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Product Overview

Description

The olfactory bulb is located in the forebrain of vertebrates and its function is to receive nerve endings/input from the nasal cavity. The sense of smell is related to the nerve tissue of the olfactory bulb. Immortalized mouse olfactory bulb cells (OBC13) are immortalized using a non-replicating retrovirus carrying the avian Myc gene. It is a sister derivative of immortalized mouse olfactory bulb cells (OBC1). The cells exhibited GalC (marker of oligodendrocyte lineage) but no NF (neurofilament marker). Voltage-dependent potassium channels are also expressed. OBC13 cells have been shown to form tumors in animal models and therefore have tumorigenic ability. It is a valuable in vitro research tool related to olfactory bulb function and biology.

Cell Types

Olfactory system-related Cells

Applications

Cell Culture

Species

Mouse

Properties

Size

>1x10^6 Cells

Growth Pattern

Adherent

Morphology

Flattened/Dendrite

Immortalization Method

Infection with retrovirus containing avian Myc gene (pneoMLV)

Freeze Medium

90%FBS+10%DMSO

Tissue Source

Brain

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

• Each vial contains ≥ 1X10^6 viable cells.
• Cells are tested by PCR and are negative for Hepatitis A, B, C, HPV, Herpes and HIV-1 & 2 viruses.
• Cells are negative for mycoplasma contamination.

Publications