Mouse Olfactory Bulb Cells (Obc1), Immortalized

[CAT#: NCL-2108P121]

Species:: Mouse

Applications:: Cell Culture

Cell Types:: Olfactory system-related Cells

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Product Overview

Description

The olfactory bulb is located in the forebrain of vertebrates and its function is to receive nerve endings/input from the nasal cavity. The sense of smell is related to the nerve tissue of the olfactory bulb. Immortalized mouse olfactory bulb cells (OBC1) are immortalized using a non-replicating retrovirus carrying the avian Myc gene. The cells exhibit NF (neurofilament) and GalC (marker of the oligodendrocyte lineage) markers. OBC1 cells have been shown to form tumors in animal models and therefore have tumorigenic ability. It is a valuable in vitro tool for research related to olfactory bulb function and biology.

Cell Types

Olfactory system-related Cells

Applications

Cell Culture

Species

Mouse

Properties

Size

>1x10^6 Cells

Growth Pattern

Adherent

Morphology

flat/dendritic protrusions

Immortalization Method

Infection with retrovirus containing avian Myc gene (pneoMLV)

Freeze Medium

90%FBS+10%DMSO

Tissue Source

Brain

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

• Each vial contains ≥ 1X10^6 viable cells.
• Cells are tested by PCR and are negative for Hepatitis A, B, C, HPV, Herpes and HIV-1 & 2 viruses.
• Cells are negative for mycoplasma contamination.

Publications