iNeu™ Human Neural Stem Cells - Spinocerebellar Ataxia Type 2 (SCA2) Patient, Donor 59
[CAT#: NRZP-0622-ZP86]
Q&As(4)
Human iPSC-derived neural stem cells from patients with spinocerebellar ataxia type 2 (SCA2)
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Neural Stem Cells
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Product Overview
Description
Spinocerebellar ataxia is a rare inherited autosomal dominant disorder that causes progressive cerebellar ataxia. There are different subtypes of the disease, which are based on mutations in the Ataxin gene family as well as in the calcium channel subunit genes. Creative Biolabs cell lines derived from spinocerebellar ataxia patients as well as familial and unaffected controls are excellent models for studying this rare genetic disorder. Creative Biolabs now offers custom human iPSC-derived brain cells or cardiomyocytes derived from patients with spinocerebellar ataxia.
Cell Types
Neural Stem Cells
Applications
Cell Culture
Relevant Diseases
Ataxia
Species
Human
Properties
Tissue Source
Fibroblasts
Shipping
Dry ice
Storage
Liquid Nitrogen Vapor Phase
Research Use Only
For research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.
Donor Information
Gender
Female
Donor Age
Unknown
Donor Health
Disease
Additional Donor Information
Gene Type: ATXN2
Publications
Publications (0)
Neural Cell Lines
Customer Reviews and Q&As
Q&As
Could you provide information on the reagents used for thawing and maintaining neuronal stem cells in culture, as well as for their differentiation into mature neurons?
We are pleased to offer three standard neuronal protocols for NSCs: the Enriched Cortical Neuron protocol, Striatal Neuron protocol, and Spontaneous Differentiation protocol. If you let us know which specific protocol you are interested in, we will be happy to provide you with further guidance.
What specific genetic stability tests were performed on the neuronal stem cells (NSCs)?
They undergo a comprehensive set of quality control (QC) tests. These tests encompass sterility assessment, Sendai clearance (where applicable), viability evaluation, karyotyping, confirmation of genetic mutations, and phenotyping against a range of pluripotency markers such as SSEA-1, SSEA-3, SSEA-4, NANOG, OCT3/4, and TRA-1-60.
What pluripotency tests are conducted on the NSCs?
We have thoroughly validated the pluripotency of our iPSCs by differentiating them into a diverse array of cell types, including NSCs, cortical neurons, astrocytes, microglia, monocytes, macrophages, interneurons, dopaminergic neurons, striatal neurons, sensory neurons, motor neurons, and atrial & ventricular cardiomyocytes.
Do you have any NSCs available from donors who do not have any health-related conditions?
We do offer iNeu™ Human Neural Stem Cells. These cells are derived from fibroblasts obtained from a 74-year-old male donor (Cat.#NCL-2101-ZP04) and a 64-year-old female donor (Cat.#NCL-2101-ZP05).
For Research Use Only. Not For Clinical Use.
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