NeuroMab™ Anti-pTau Antibody(NRP-0422-P1741)
[CAT#: NRP-0422-P1741]
Functional antibody against Human, Mouse pTau
- Host Species:
- Humanized
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; ELISA; Inhib; In Vivo; In Vitro
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
NRP-0422-P174 antibody targets phosphorylated serine at position 422 Tau protein.
Immunogen
P-S422
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Humanized
Applications
WB; ELISA; Inhib; In Vivo; In Vitro
Relevant Diseases
Alzheimer's Disease
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
pTau
Official Name
pTau
Full Name
phosphorylated tau
Alternative Names
MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Product Pictures
FuncS
Figure 1 HEK293 cells and in vitro vaccination.
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Figure 2 Depletion of tau for inoculation assay (HEK293).
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Figure 3: Inoculation experiments with depleted material (HEK293)
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Figure 4. Hippocampal tau pathology in rTg4510 mice inoculated with immunodeficient rTg4510 material.
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Figure 5. Hippocampal tangle pathology in vaccinated rTg4510 mice treated with D1.2.
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Figure 6 Tau removal (HEK293) for inoculation experiments
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Figure 7 Pathology of hippocampal tangles in rTg4510 mice inoculated with D1.2
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Figure 8 Quantification of aggregated tau after immunodeficiency reduction
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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