Product
NeuroMab™ Rat Anti-Myelin Protein Zero Monoclonal Antibody (CBP2231)
[CAT#: NAB2010133LS]
Anti-Myelin Protein Zero Monoclonal Antibody
- Host Species:
- Rat
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Myelin protein zero (MPZ), is a membrane glycoprotein mainly expressed in the peripheral nervous system (PNS). It is the major structural component of the myelin sheath, and accounts for at least 50% of all proteins in the PNS. MPZ is expressed by Schewann cells. Mutations in MPZ have been associated with myelin deficiency, which may lead to neuropathies including charcot-Marie-Tooth and Dejerine-Sottas diseases.
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG2b, κ
Clone Number
CBP2231
Applications
WB; IHC-P
Application Notes
WB (1-5 µg/mL); IHC (5-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1656
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Chiò A and Lauria G. 2016. Lancet Neurol. 15(1):12
2. Brennan KM, et al. 2015. Neurosci Lett. 596:14
3. Tazir M, et al. 2014. J Neurol Sci. 347(1-2):14
2. Brennan KM, et al. 2015. Neurosci Lett. 596:14
3. Tazir M, et al. 2014. J Neurol Sci. 347(1-2):14
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
