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Creative Biolabs

Mouse Anti-mGlu1 Monoclonal Antibody (CBP2369)

[CAT#: NAB2010379LS]

Anti-mGlu1 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
WB

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Product Overview

Description

Glutamate Metabotropic Receptor 1, also known as GRM1, is a G protein-coupled receptor that belongs to the group 1 metabotropic glutamate receptor family (mGluR1). GRM1 is an excitatory neurotransmitter receptor involved in hippocampal long-term potentiation and cerebellar long-term depression as demonstrated in an in vivo mouse knockout model of GRM1.These animals also display impaired motor function despite normal brain structure and anatomy compared to their wild type littermates.

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2369

Applications

WB

Application Notes

WB (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

mGlu1

Official Name

GRM1

Full Name

glutamate receptor, metabotropic 1

Alternative Names

GRM1; GPRC1A; MGLU1; MGLUR1; PPP1R85; SCAR13; glutamate metabotropic receptor 1; SCA44

Gene ID

2911(Human); 14816(Mouse); 24414(Rat)

Uniprot ID

Q13255(Human); P97772(Mouse); P23385(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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