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Creative Biolabs

NeuroMab™ Mouse Anti-Human HSP70 Monoclonal Antibody (CBP2513)

[CAT#: NAB2010655LS]

Anti HSP70 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; IHC-P

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Product Overview

Description

Hsp70 is a member of the Hsp family of highly conserved proteins that play a role in a number of important functions. Their synthesis is increased upon environmental stress. They function by acting as molecular chaperones, facilitating protein refolding and preventing protein aggregation. It has been reported that extracellular Hsp70 also exhibits regulatory effects on innate and acquired immunity.

Immunogen

This monoclonal antibody was raised against human recombinant HSP-70 protein over expressed in E. coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP2513

Applications

WB; IHC-P

Application Notes

WB (1-10 µg/mL) IHC-P (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1839
Product Properties

Form

Liquid

Formulation

Ammonium sulfate precipitated tissue culture supernatant.

Concentration

Batch Dependent

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

HSP70

Official Name

HSP70

Full Name

Heat shock 70kDa protein 1A

Alternative Names

HSP70; Heat shock 70kDa protein 1A

Gene ID

15511(Human); 3304(Mouse); 24472(Rat)

Uniprot ID

P0DMV9(Human); P17879(Mouse); P0DMW0(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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