NeuroMab™ Mouse Anti-IL-1 Beta Monoclonal Antibody (CBP2536)

Product Overview

Description

Mouse anti-sheep interleukin-1 beta. Mouse anti-sheep interleukin-1β antibody, recognizes sheep interleukin-1β, and does not cross-react with sheep IL-6, IL-8, TNFα or MCP-1.

Immunogen

Recombinant sheep IL-1 Beta.

Species Reactivity

Sheep; Goat; Bovine; Horse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2536

Applications

ELISA; FC; IHC-Fr; WB

Application Notes

FC: 1/10

Relevant Diseases

Amyotrophic Lateral Sclerosis; Frontotemporal Dementia

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1855

Product Properties

Form

Liquid

Formulation

PBS, 0.09% Sodium Azide

Preservatives

YES

Concentration

1 mg/ml

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Il-1β

Official Name

IL1B

Full Name

Interleukin 1 beta

Alternative Names

IL1B; IL-1; IL1-BETA; IL1F2; interleukin 1 beta; IL1beta

Gene ID

16176(Human)

Uniprot ID

P10749(Human)

References

1. Bannerman, D.D. et al. (2004) Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection.
2. Simojoki, H. et al. (2011) Innate immune response in experimentally induced bovine intramammary infection with Staphylococcus simulans and S. epidermidis.
3. Redondo, E. et al. (2014) Induction of interleukin-8 and interleukin-12 in neonatal ovine lung following experimental inoculation of bovine respiratory syncytial virus.

Publications