NeuroMab™ Mouse Anti-CD80 Monoclonal Antibody (CBP2551)

Product Overview

Description

The mouse anti-bovine CD80 antibody recognizes the bovine CD80 cell surface antigen expressed by dendritic cells, activated macrophages and activated B cells. During the initial immune response, CD80 plays a key role in co-stimulating T cells.

Species Reactivity

Bovine; Sheep

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2551

Applications

Application Notes

FC: 1/10

Relevant Diseases

Alzheimer's Disease; Neurodegenerative Disease

Research Areas

Neuroregeneration

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1860

Product Properties

Form

Liquid

Formulation

PBS, 0.09% Sodium Azide, 1% BSA

Preservatives

YES

Purification

Affinity chromatography

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD80

Official Name

CD80

Full Name

CD80 Molecule

Alternative Names

CD80 Molecule; CD80 Antigen (CD28 Antigen Ligand 1, B7-1 Antigen); B-Lymphocyte Activation Antigen B7; CTLA-4 Counter-Receptor B7.1; Activation B7-1 Antigen; CD28LG1; CD28LG; LAB7; BB1;

Gene ID

941(Human); 12519(Mouse)

Uniprot ID

P33681(Human); Q00609(Mouse)

References

1. Glew, E.J. et al. (2003) Differential effects of bovine viral diarrhoea virus on monocytes and dendritic cells.
2. Epardaud, M. et al. (2004) Enrichment for a CD26hi SIRP- subset in lymph dendritic cells from the upper aero-digestive tract.
3. Bonneau, M. et al. (2006) Migratory monocytes and granulocytes are major lymphatic carriers of Salmonella from tissue to draining lymph node.

Publications