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Creative Biolabs
Product

Mouse Anti-Human CD107b Monoclonal Antibody (CBP3805)

[CAT#: NAB2012273LS]

Anti-CD107b Monoclonal Antibody [Alexa Fluor 594 ]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC-P

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Product Overview

Description

CD107b, also known as LAMP-2, is a 105 kD, highly gylcosylated, type I transmembrane protein. CD107b is expressed in lysosomal/endosomal membranes in nearly all cells, and on the surface of activated platelets, activated lymphocytes and some tumor cell lines. CD107b is known to have roles in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation.

Immunogen

Adult human adherent spleen cells

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3805

Applications

IHC-P

Application Notes

IHC-P (5-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD107b

Official Name

LAMP2

Full Name

Lysosomal associated membrane protein 2

Alternative Names

LAMP2; CD107b; LAMP-2; LAMPB; LGP110; lysosomal associated membrane protein 2; LGP-96; DND

Gene ID

2930 (Human); 16784 (Mouse)

Uniprot ID

P13473 (Human); P17047 (Mouse)
References

1. Chen J, et al. 1985. J. Biol. Chem. 101:85.
2. Kain R, et al. 2008. Nat. Med. 14:1088.
3. Roark EA, et al. 2008. PLoS ONE 3:e3538.
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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