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Creative Biolabs
Product

Mouse Anti-Rat CD107b Monoclonal Antibody (CBP4296)

[CAT#: NAB210167LS]

Anti-CD107b Monoclonal Antibody [Biotin]

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
IHC-P

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Product Overview

Description

CD107b, also known as LAMP-2, is a 105 kD, highly glycosylated, type I transmembrane protein. CD107b is expressed in lysosomal/endosomal membranes in nearly all cells, on the surface of activated platelets, activated lymphocytes and some tumor cell lines. LAMP-2 is known to have roles in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation.

Immunogen

Balb/c 3T3 mouse embryo fobroblast tissue culture cell glycoproteins. It has been mapped to the N-terminus of LAMP 2.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP4296

Applications

IHC-P

Application Notes

IHC-P (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Biotin
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD107b

Official Name

LAMP2

Full Name

Lysosomal associated membrane protein 2

Alternative Names

LAMP2; CD107b; LAMP-2; LAMPB; LGP110; lysosomal associated membrane protein 2; LGP-96; DND

Gene ID

Uniprot ID

P13473 (Human); P17047 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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