Human 1321N1/P2Y4 Stable Cell Line

[CAT#: NCL20120107CR]

P2Y4 Purinergic Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

P2Y4 is a receptor that is activated by UTP specifically. Activation of P2Y4 results in increased inositol phosphate formation and mobilization of intracellular calcium. Although selective antagonists for P2Y4 are still lack, P2Y4 may play an important role in vascular diseases, and immunomodulatory intervention.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR; Neural Cell

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

DMEM, 10% FBS, 250 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

P2Y4

Family

P4Y receptor

Strain

1321N1/P2Y4 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

P2Y4

Official Name

P2Y4

Alternative Names

P2Y4R; P2Y purinoceptor 4; HP2U; P2RU1; P2U; P2U1; P2UR; P2Y2R; purinergic receptor P2Y G-protein coupled 4

Gene ID

5030(Human); 57385(Mouse); 63843(Rat)

Uniprot ID

P51582(Human); Q9JJS7(Mouse); O35811(Rat)

References

1. Mi, G., Liu, S., Zhang, J., Liang, H., Gao, Y., Li, N.,.. & Yang, Z. (2017). Levo-tetrahydroberberrubine produces anxiolytic-like effects in mice through the 5-HT 1A receptor. PloS one, 12(1), e0168964.

Publications