Human CHO-K1/OXTR Stable Cell Line

[CAT#: NCL20120134CR]

Oxytocin Receptor Stable Cell Line

Species:: Human

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

Oxytocin receptors are expressed in the uterus and in mammary glands, where they mediate functions related to partutition, such as contraction of the uterine myometrium during labor and milk letdown. In addition, oxytocin receptors are expressed in a variety of other peripheral tissues and in the brain, where oxytocin mediates a variety of functions.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 400 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

OT/OXTR

Family

Vasopressin and oxytocin receptor

Strain

OXTR Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

OXTR

Official Name

OXTR

Alternative Names

OT receptor; OT-R; OTR1; OTR; Oxytocin receptor

Gene ID

5021(Human); 18430(Mouse); 25342(Rat)

Uniprot ID

P30559(Human); P97926(Mouse); P70536(Rat)

References

1. Pierce, M. L., French, J. A., & Murray, T. F. (2020). Comparison of the pharmacologic profiles of arginine vasopressin and oxytocin analogs at marmoset, titi monkey, macaque, and human oxytocin receptors. Biomedicine & Pharmacotherapy, 125, 109832. 2.

Publications