iNeu™ Human Neural Stem Cells - Spinocerebellar Ataxia Type 2 (SCA2) Patient, Donor 58
[CAT#: NRZP-0622-ZP85]
Q&As(4)
Human iPSC-derived neural stem cells from patients with spinocerebellar ataxia type 2 (SCA2)
- Species:
- Human
- Applications:
- Cell Culture
- Cell Types:
- Neural Stem Cells
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Product Overview
Description
Spinocerebellar ataxia is a rare inherited autosomal dominant disorder that causes progressive cerebellar ataxia. There are different subtypes of the disease, which are based on mutations in the Ataxin gene family as well as in the calcium channel subunit genes. Creative Biolabs cell lines derived from spinocerebellar ataxia patients as well as familial and unaffected controls are excellent models for studying this rare genetic disorder. Creative Biolabs now offers custom human iPSC-derived brain cells or cardiomyocytes derived from patients with spinocerebellar ataxia.
Cell Types
Neural Stem Cells
Applications
Cell Culture
Relevant Diseases
Ataxia
Species
Human
Properties
Tissue Source
Fibroblasts
Shipping
Dry ice
Storage
Liquid Nitrogen Vapor Phase
Research Use Only
For research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.
Donor Information
Gender
Male
Donor Age
58
Donor Health
Disease
Additional Donor Information
Gene Type: ATXN2
Publications
Publications (0)
Neural Cell Lines
Customer Reviews and Q&As
Q&As
Which reagents are utilized for the thawing and maintenance of neuronal stem cells in culture, as well as for their differentiation into mature neurons?
We offer three standard neuronal protocols for NSCs including the Enriched Cortical Neuron protocol, Striatal Neuron protocol, and Spontaneous Differentiation protocol. If you specify which protocol you're interested in, we would be delighted to provide you with further guidance.
What specific genetic stability tests were conducted on the neuronal stem cells (NSCs)?
Regarding our iPSCs, they undergo comprehensive quality control (QC) tests. These tests include assessments for sterility, Sendai clearance (where relevant), viability, karyotyping, confirmation of genetic mutations, and phenotyping against a range of pluripotency markers such as SSEA-1, SSEA-3, SSEA-4, NANOG, OCT3/4, and TRA-1-60.
Which pluripotency tests were carried out on the NSCs?
We have validated the pluripotency of our iPSCs by differentiating them into a wide range of cell types, including NSCs, cortical neurons, astrocytes, microglia, monocytes, macrophages, interneurons, dopaminergic neurons, striatal neurons, sensory neurons, motor neurons, and atrial & ventricular cardiomyocytes.
Are there any NSCs available from donors without any health-related issues?
We do have iNeu™ Human Neural Stem Cells available. These cells originate from fibroblasts obtained from a 74-year-old male donor (Cat.#NCL-2101-ZP04) and a 64-year-old female donor (Cat.#NCL-2101-ZP05).
For Research Use Only. Not For Clinical Use.
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