Creative Biolabs

Mouse alpha-GalA-/o Schwann Cells, Immortalized

[CAT#: NCL-2105-P198-AM]

These cells can be used for disease modeling, drug screening and toxicology testing.

Species:
Mouse
Applications:
Cell Assay
Cell Types:
Schwann Cell

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Description
Immortalized mouse α-GalA-/or Schwann cell (1089C1) is a spontaneously immortalized cell line from Fabry mice. The Gla gene allele of 1089C1 has been disrupted and exhibits a unique Schwann cell morphology And biochemical phenotype (insufficient α-galactosidase activity). This cell line can be used as a mouse model for Fabry disease research.

Expression profile
S100, laminin, p75NTR, GFAP, fructosylceramide (Gb3)
Cell Types
Schwann Cell
Applications
Cell Assay
Species
Mouse
Freeze Medium
90% FBS+10% DMSO
Tissue Source
Brain
Cell Purity
>95%
Cell Viability
>90%
Mycoplasma Testing
Negative
Sterility Testing
The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Shipping
Frozen on dry ice
Storage
Liquid nitrogen immediately upon delivery
Research Use Only
For research use only
Quality Control
1) RT-PCR; 2) Immunocytochemical analysis; 3) Assaying of α-galactosidase activity and protein determination
For Research Use Only. Not For Clinical Use.
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