Creative Biolabs

Mouse Schwann Cells (IMS32), Immortalized

[CAT#: NCL-2105-P224-AM]

These cells can be used for disease modeling, drug screening and toxicology testing.

Species:
Mouse
Applications:
Cell Assay
Cell Types:
Schwann Cell

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Description
Immortalized mouse Schwann cells express glial cell markers (S100, GFAP, p75NTR); transcription factors involved in Schwann cell development and peripheral myelination (Krox20, Oct6, PAX3 and SOX10); and neurotrophic factors (NGF, BDNF, GDNF, and CNTF. In the presence of growth factors, such as PDGF-BB, aFGF, bFGF or TGF-β1, these cells exhibit mitogenic responses. IMS32 cells can be used to study the mechanisms involved in peripheral nerve regeneration , And as an in vitro model for evaluating the pathogenesis of neurological diseases.

Species description: ICR mouse
Cell Types
Schwann Cell
Applications
Cell Assay
Application Notes
Cell Cuture:
PriNeu III medium (NCL-2105-P169-AM)
Fetal bovine serum (NCL-2105-P170-AM)
Penicillin/Streptomycin Solution (NCL-2105-P172-AM)
Species
Mouse
Freeze Medium
90% FBS+10% DMSO
Tissue Source
Brain
Cell Purity
>95%
Cell Viability
>90%
Mycoplasma Testing
Negative
Sterility Testing
The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Shipping
Frozen on dry ice
Storage
Liquid nitrogen immediately upon delivery
Research Use Only
For research use only
Quality Control
Immune response to cell markers
For Research Use Only. Not For Clinical Use.
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