Product
NeuroMab™ Mouse Anti-CALB2 Monoclonal Antibody (CBP2788)
[CAT#: NAB20101865CR]
Mouse Monoclonal (2D7A9) to CALB2
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Porcine; Rat
- Applications:
- IHC; WB; ELISA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Calbindin 2 (calretinin) is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.
Expression Host
Mammalian cells
Immunogen
Calretinin fusion protein Ag2924
Species Reactivity
Human; Mouse; Porcine; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2788
Applications
IHC; WB; ELISA
Application Notes
IHC : 1:20-1:200; WB : 1:500-1:1000
Research Areas
Metabolism
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1894
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Sano, H., Namekata, K., Kimura, A., Shitara, H., Guo, X., Harada, C.,... & Harada, T. (2019). Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma. Cell death & disease, 10(2), 1-14. 2. Akaiwa, K., Namekata, K., Azuchi, Y., Sano, H., Guo, X., Kimura, A.,... & Harada, T. (2018). Topical ripasudil suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma. Investigative Ophthalmology & Visual Science, 59(5), 2080-2089. 3. Zhou, H., Su, J., Hu, X., Zhou, C., Li, H., Chen, Z.,... & Zhou, Y. (2020). Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice. Cell.
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
