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Creative Biolabs

Human CHO-K1/MT2/Gα15 Stable Cell Line

[CAT#: NCL20120089CR]

Melatonin MT2 Receptor Stable Cell Line

Species:
Human
Applications:
GPCR Screening
Cell Types:
Other Cells

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Product Overview

Description

Melatonin plays a key role in the synchronisation of circadian and seasonal functions with cyclic environmental variations. In mammals, two melatonin receptors, MT1 and MT2, have been cloned. Activation of MT2 melatonin receptors phase shift circadian rhythms of neuronal firing in the suprachiasmatic nucleus, inhibit dopamine release in retina, induce vasodilation and inhibition of leukocyte rolling in arterial beds, and enhance immune responses.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR

Species

Human
Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

Ham's F12, 10% FBS, 100 μg/ml Hygromycin B, 400 μg/ml G418

Freeze Medium

45% culture medium, 45% FBS, 10% DMSO

Receptor

MT2/MTNR1B

Family

Melatonin receptor

Strain

MT2/Gα15 Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.
Target Details

Target

MT2

Official Name

MT2

Alternative Names

MT2 receptor; Mel1b; ML1B; Mel1b-r; mel1b melatonin receptor; mel1b receptor; melatonin receptor 1B; melatonin receptor type 1B; Mel1b; Mt2

Gene ID

4324(Human)

Uniprot ID

P51511(Human)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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