iNeu™ Human Dopaminergic Neuron Kit, Male

[CAT#: NRP-0322-P2267]

Species:: Human

Cell Types:: Dopaminergic Neurons

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Product Overview

Description

Creative Biolabs has developed an efficient integration-free, small-molecule-based method to differentiate high-quality dopaminergic (DOPA) neurons from human iPSCs. Differentiated dopamine neurons recapitulate the phenotypic and functional parameters of primary and in vivo dopaminergic neurons. These highly purified cells expressed high levels of the dopaminergic neuronal biomarker TH.

To achieve the full potential of our dopa neurons, we also offer an optimized dopa neuron basal medium and dopa neuron supplement to support dopaminergic neurons in culture robust maintenance and functionality.

These iPSC-differentiated Dopa neurons can be used as a control line to compare the phenotype and function of patient-derived, genome-edited iPSC-derived Dopa neurons for drug screening applications. Dopaminergic neurons can also be used in neurotoxicity assays.

Cell Types

Dopaminergic Neurons

Species

Human

Properties

Size

1 kit

Components

iPSC-Derived Dopaminergic Neurons; African-American Male Line ≥1x10^6 cells/ vial
DOPA Neuron Basal Media 100 mL
DOPA Neuron Supplement 1 mL

Culture Medium

Feeder free

Tissue Source

Dermal Fibroblasts

Shipping

Dry ice

Storage

Store the components of the kit at the appropriate storage conditions as indicated in the media and materials table, immediately upon arrival. Shelf-life of the product is contingent upon proper storage conditions

Research Use Only

For research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.

Quality Control

Each lot of iPSC-derived human dopaminergic neurons has been tested for growth, viability and purity (≥70%) following recovery from cryopreservation. In addition, each lot has been tested for expression of DOPA neuron markers and for the absence of mycoplasma and pathogens.

Donor Information