Mouse CHO-K1/ADORA2A Receptor Stable Cell Line

[CAT#: NCL20120015CR]

Adenosine A2A Receptor Stable Cell Line

Species:: Mouse

Applications:: GPCR Screening

Cell Types:: Other Cells

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Product Overview

Description

ADORA2A is Gs-coupled GPCRs expressed in the thymus gland, heart, lung, kedney, brain, platelets, spleen and leukocytes. ADORA2A down-regulates chemokine receptor function and inhibits platelet aggregation. ADORA2A antagonists may be useful as therapy for Parkinson's disease.

Cell Types

Other Cells

Applications

GPCR Screening

Research Areas

GPCR; Neural Stem Cell

Species

Mouse

Properties

Size

>1x10^6 Cells

Form

Frozen cells

Culture Medium

F-12K, 10% FBS, 450 μg/ml Zeocin

Freeze Medium

95% complete growth medium, 5% DMSO

Receptor

ADORA2a

Family

Adenosine receptor

Strain

mouse ADORA2A Cell Line

Cell Purity

>95%

Shipping

Dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Warnings

Store under recommended storage conditions (liquid nitrogen). Do not expose to high temperature. After expiration, discard all remaining reagents.

Target Details

Target

A2AR

Official Name

A2AR

Alternative Names

RDC8; A2-AR; adenosine receptor A2a

Gene ID

135(Human); 11540(Mouse); 25369(Rat)

Uniprot ID

P29274(Human); Q60613(Mouse); P30543(Rat)

References

1. Li, T., Ju, E., & Gao, S. J. (2019). Kaposi sarcoma-associated herpesvirus miRNAs suppress CASTOR1-mediated mTORC1 inhibition to promote tumorigenesis. The Journal of clinical investigation, 129(8). 2. Huang, X., Zhang, Q., Lou, Y., Wang, J., Zhao, X., Wang, L.,.. & Liang, T. (2019). USP22 deubiquitinates CD274 to suppress anticancer immunity. Cancer immunology research, 7(10), 1580-1590. 3. Cheng, Z., Zhang, X., Huang, P., Huang, G., Zhu, J., Chen, F.,.. & Wang, X. (2020). Nup96 and HOS1 are mutually stabilized and gate CONSTANS protein level, conferring long-day photoperiodic flowering regulation in Arabidopsis. The Plant Cell, 32(2), 374-391.

Publications