NeuroMab™ Anti-Notch 1 Antibody(NRP-0422-P1183)

Product Overview

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

FC; In Vitro; Inhib

Relevant Diseases

Alzheimer's Disease; Epilepsy; Pain

Product Properties

Preservatives

BSA Free

Concentration

1mg/mL

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

Notch1

Official Name

NOTCH1

Full Name

NOTCH1

Alternative Names

Notch 1; Translocation-Associated Notch Protein TAN-1; TAN1; HN1; Notch (Drosophila) Homolog 1 (Translocation-Associated); Notch Homolog 1; Translocation-Associated (Drosophila); Notch Homolog 1; Translocation-Associated;

Gene ID

4851 (Human); 18128 (Mouse); 25496 (Rat)

Uniprot ID

P46531 (Human); Q01705 Mouse (Mouse); Q07008 Rat (Rat)

Product Pictures

FuncS

Figure 1: Antibodies against NOTCH1 EGF13 and EGF4 do not effectively block ligand binding.

NOTCH1 expressing HEK 293 cells were incubated with either DLL4-Fc (left) or JAG1-Fc (right) in the presence of anti-NOTCH1 antibodies (13M57, 31M103, 31M106, or 31M108) or control anti-DLL4 (21M18) or anti-JAG1 (64M14) antibodies.

Publications