NeuroMab™ Anti-NOTCH2 BBB Shuttle Antibody(NRZP-1022-ZP3251)
[CAT#: NRZP-1022-ZP3251]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC; Inhib; Block; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
FC; Inhib; Block; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease; Epilepsy; Pain
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
NOTCH2
Official Name
NOTCH2
Full Name
Neurogenic locus notch homolog protein 2
Alternative Names
NOTCH2; AGS2; HJCYS; hN2; Notch-2; notch 2; notch receptor 2
Product Pictures
FuncS
Figure 1: Effect of NOTCH2 monoclonal antibody 59M07 on colon tumor growth.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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