NeuroMab™ Anti-Tau Antibody(NRP-0422-P1706)

Product Overview

Description

NRP-0422-P1706 reacted on different tau forms and was found to be a pan-like antibody such as Tau-5 not dependent on phosphorylation or hyperphosphorylation for optimal recognition.

Immunogen

full-length human tau (longest isoform. 2N4R; 441 amino acids)

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; ELISA; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease

Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only

Target

Tau

Official Name

Tau

Full Name

Tau

Alternative Names

CD14

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)

Product Pictures

FuncS

Figure 1. Graph illustrating counts of beads coupled to ADx202; Y-axis represents counts and X-axis represents diameter in µm.

FuncS

Figure 2. Graph illustrating counts of beads coupled to Tau-5; Y-axis represents counts and X-axis represents diameter in μm.

FuncS

Figure 3: Graph representing MAGPIX median fluorescence intensity

(MFI) measurement of beads coupled with ADx202 and Tau -5 using a phycoerythrin- labeled anti-mouse IgG detection antibody (anti-mouse-PE). The X-axis represents the concentration of the ph ycoery th rin-1 abel ed anti-mouse IgG detection antibody: the Y-axis represents the MFI measurement. These data illustrate that the amount of antibody coupled per bead is higher for Tau5 than for ADx202.

FuncS

Figure 4: Graph representing MAGPIX median fluorescence intensity (MFI) measurements of beads conjugated to ADx202 and Tau-5 using the antigen human tau-441.

The X-axis represents the concentration of rPeptide441 in pg/mL: the Y-axis represents the MFI measurement. These data illustrate that ADx202 captures rPeptide tau441 more efficiently then Tau5.

Publications