Mouse Anti-Human ITGAM Monoclonal Antibody (CBP1548)

Product Overview

Description

Mouse anti-human MAdCAM-1 antibody, clone CA102.2C1 recognizes human mucosal membrane address protein cell adhesion molecule-1, also known as MAdCAM-1. Human MAdCAM-1 is a single-pass type 1 transmembrane glycoprotein of 382 amino acids and about 40-60 kDa expressed by vascular endothelium. Mouse anti-human MAdCAM-1 antibody, clone CA102.2C1 has been reported to block the binding of human cells expressing α4Beta7. Immobilized MAdCAM-1 in vitro.

Immunogen

Bacterially expressed human MAdCAM-1.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP1548

Applications

ELISA; WB

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS

Preservatives

Preservative Free

Concentration

1 mg/ml

Purification

Purified IgG prepared by affinity chromatography on Protein A.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Target

CD11b

Official Name

ITGAM

Full Name

Integrin alpha M

Alternative Names

ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M

Gene ID

3684 (Human); 16409 (Mouse); 25021 (Rat)

Uniprot ID

P11215 (Human); P05555 (Mouse)

References

1. Eksteen, B. et al. (2006) Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10. 2. Liaskou, E. et al. (2011) Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity. 3. Krissansen, G. et al. (2007) Monoclonal Antibodies That Recognise Mucosal Addressin Cell Adhesion Molecule-1 (Madcam-1), Soluble Madcam-1 And Uses Thereof 4. Liaskou, E. (2010) MAdCAM-1 Expression and Function in Human Liver.

Publications