Product
Mouse Anti-ITGAM Monoclonal Antibody (CBP1531)
[CAT#: NAB2007FY332]
Mouse Monoclonal [W0031] to ITGAM
- Host Species:
- Mouse
- Species Reactivity:
- Human; Hamster; Rat; Marmoset
- Applications:
- ELISA; IHC-P; WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
Mouse anti-human synaptophysin antibody, clone SP15 recognizes human synaptophysin, also known as major synaptophysin p38. Synaptophysin is a 313 amino acid synaptic vesicle-associated protein of about 38 kDa, containing a single exotic domain. Synaptophysin is expressed ubiquitously in the synaptic vesicle membrane. It is the most abundant protein in the synaptic vesicle membrane and participates in the regulation of endocytosis (Kwon et al., 2011).
The loss and atypical expression of synaptophysin is noted in cases such as Huntington's disease (Goto and Hirano 1990) and Alzheimer's disease (Masliah et al. 1989). Mutations in the synaptophysin gene have been identified and led to a condition of mental retardation, X-linked 96.
The loss and atypical expression of synaptophysin is noted in cases such as Huntington's disease (Goto and Hirano 1990) and Alzheimer's disease (Masliah et al. 1989). Mutations in the synaptophysin gene have been identified and led to a condition of mental retardation, X-linked 96.
Immunogen
Crude human synaptic immunoprecipitate.
Species Reactivity
Human; Hamster; Rat; Marmoset
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgM
Clone Number
CBP1531
Applications
ELISA; IHC-P; WB
Application Notes
IHC-P (1/25); WB (1/500)
Research Areas
Growth and Development
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS
0.09% Sodium Azide
0.09% Sodium Azide
Concentration
1 mg/ml
Purification
Purified IgM prepared by ammonium sulphate precipitation.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Target
References
1. Honer, W.G. et al. (1992) Characterization of a synaptic antigen of interest in neuropsychiatric illness.
2. Honer, W.G. et al. (1989) Monoclonal antibodies to study the brain in schizophrenia.
3. Masliah, E. et al. (1994) Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus.
4. Del Bigio, M.R. et al. (2003) Chronic hydrocephalus in rats and humans: white matter loss and behavior changes.
2. Honer, W.G. et al. (1989) Monoclonal antibodies to study the brain in schizophrenia.
3. Masliah, E. et al. (1994) Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus.
4. Del Bigio, M.R. et al. (2003) Chronic hydrocephalus in rats and humans: white matter loss and behavior changes.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
