NeuroMab™ Anti-Tau Antibody (NRP-0422-P1694)
Functional antibody against Human Tau
- Host Species:
- Humanized
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Applications
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
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Research Use Only
Figure 1 Western blotting (WB) analysis of general Tau antibody display in brain lysates from Alzheimer's disease (AD) and matched control donors.
Figure 2 Tau capture ELISA.
Figure 3 shows the pharmacokinetics in mice following a single 10mg/kg intravenous or intraperitoneal injection of anti-Tau antibody.
Figure 4 shows that the change over time is flat in macaques following a single IV injection of 50 mg/kg of specific antibodies.
Figure 5 shows the concentration of antibodies in the hippocampus of rhesus monkeys at various time points after a single IV injection of 50 mg/kg of the indicated antibodies in rhesus monkeys.
Figure 6 shows, on a logarithmic scale, specific antibody injections at different time points after a single IV antibody concentration of 50 mg/kg in the macaque brain.
Figure 7 shows the concentration of total Tau in plasma and the concentration of macaque starch antibody in blood after a single IV injection of 50 mg/kg of a specific antibody in macaques.
Figure 8 is the plasma antibody concentration after a single intravenous injection of 50 mg/kg specific antibody in rhesus monkeys.
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