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Creative Biolabs

Mouse Anti-MAP Tau Monoclonal Antibody (CBP6659)

[CAT#: NAB2007FY1520]

Mouse Monoclonal to MAP Tau

Host Species:
Mouse
Species Reactivity:
Human; Rat; Mouse
Applications:
WB; IF

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Product Overview

Description

MAP-τ is a microtubule-associated protein or a low molecular weight member of the MAP family. Several serious human diseases are associated with the accumulation of MAP-τ (often called tau protein), the most notable being the neurofibrillary tangles of Alzheimer's disease. The accumulation of tau in neurons is also a feature of chronic traumatic encephalopathy, Pick's disease and several other neurodegenerative diseases. These diseases are collectively referred to as "taupathies". A single mammalian tau gene produces at least 9 different proteins through alternate transcription. In the central nervous system, 6 isoforms in the range of 48-67kDa determined by SDS-PAGE dominate, but the larger isoforms are mainly found in the peripheral nervous system.

Immunogen

Recombinant full-length 441 amino acid human tau

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6659

Applications

WB; IF

Application Notes

WB: 1:10000
IF/ICC and IHC: 1:1000
Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Stable at 4°C for one year, for longer term store at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Tau

Official Name

MAPT

Full Name

Microtubule-associated protein tau

Alternative Names

MAPT; Microtubule-associated protein tau

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Publications

Publications (0)

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