Anti-CD11b Monoclonal Antibody (CBP3665)
[CAT#: NAB2012491LS]
Anti-CD11b Monoclonal Antibody [Alexa Fluor 594 ]
- Host Species:
- Mouse
- Species Reactivity:
- Human; African green monkey; Baboon; Chimpanzee; Common Marmoset; Cynomolgus; Rhesus; Swine
- Applications:
- FC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
CD11b is a 170 kD glycoprotein, also known as αM integrin, Mac-1α subunit, Mol, CR3 and Ly-40. CD11b is a member of the integrin family and is mainly expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and a subpopulation of T and B cells. CD11b and CD18 (β2 integrin) non-covalently bind to form Mac-1. Mac-1 plays an important role in cell-cell interactions by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b and fibrinogen.
Species Reactivity
Human; African green monkey; Baboon; Chimpanzee; Common Marmoset; Cynomolgus; Rhesus; Swine
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3665
Applications
FC
Application Notes
FCM (5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Stewart M, et al. 1995. Curr. Opin. Cell Biol. 7:690.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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