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Creative Biolabs

NeuroMab™ Anti-Tau Antibody(NRP-0422-P1698)

[CAT#: NRP-0422-P1698]

Functional antibody against Human Tau

Host Species:
Mouse; Humanized; Chimeric
Species Reactivity:
Human
Applications:
ELISA; Block; In Vitro; IHC

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Product Overview

Description

The antibody specifically binds to tau.The antibody inhibits or postpones pathology associated with tau and associated symptom deteriorates.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse; Humanized; Chimeric

Applications

ELISA; Block; In Vitro; IHC

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Tau

Official Name

Tau

Full Name

Tau

Alternative Names

CD14

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Product Pictures
ELISA

Figure 1 depicts the results of an ELISA screening assay for selected mouse monoclonal anti-tau antibodies.

Block

Figure 2 depicts the results of functional blocking measurements of anti-tau antibodies with selected mouse monoclonal antibodies.

FuncS

Figure 3 depicts disaggregation measurements of selected mouse monoclonal anti-tau antibodies.

FuncS

Figure 4 depicts the results of a tau experiment showing 3D6 and 5G8 immunocapture from human Alzheimer's disease tissue.

FuncS

Figure 5 depicts the results of experiments showing the affinity of humanized 3D6 variants for tau.

Publications

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