Tel:
Fax:
Email:
Creative Biolabs
Product

NeuroMab™ Anti-Sortilin Antibody, Clone S-20

[CAT#: NRP-0422-P2268]

Host Species:
Mouse
Species Reactivity:
Human; Mammalian
Applications:
ELISA; Inhib; In Vitro; In Vivo; Antagonist

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Inquiry

SPECIFIC INQUIRY

inquiry
Size:
Conjugation:
Endotoxin:
Purity:
Engineering:
Product Overview

Description

The antibody specifically binds one or more epitopes within a sortilin protein, e.g., human sortilin or a mammalian sortilin. The anti-sortilin antibody has a property selected from the group consisting of: increasing extracellular levels of progranulin; increasing cellular levels of progranulin; decreasing cellular levels of sortilin; inhibiting interaction between sortilin and progranulin.

Species Reactivity

Human; Mammalian

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG

Clone Number

S-20

Applications

ELISA; Inhib; In Vitro; In Vivo; Antagonist
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

>95% by SDS PAGE or HPLC

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Sortilin

Alternative Names

SORT1; Gp95; LDLCQ6; NT3; NTR3; Sortilin 1
Product Pictures
Inhib

Figure 2 is a bar graph showing the effect of different doses of MMP-12 binding proteins M08-H09 and M11-H11 on the peribronchial inflammation score in an OVA-challenged mouse model of airway inflammation.

Inhib

Figure 3 is a bar graph showing the effect of MMP-12 binding protein (M08-H09) on the infiltration of inflammatory cells into carrageenan-stimulated mouse air sacs.

Inhib

Figure 4 is a bar graph showing ELISA competition assays performed with four different MMP-12 binding proteins M08H09, M0013-G12, M0016-A11 and R0062-E11.

WB

Figure 1 shows murine MMP-12 activity (Fluo/sec) in response to increasing concentrations (nM) of MMP-12 binding protein (539B-M11H11 IgG).

Publications

Publications (0)

gift-card

Related Products
For Research Use Only. Not For Clinical Use.
Send Inquiry Send Inquiry
Inquiry Basket
compare

Send inquiry