Astrocytes are the most abundant type of neuroglia distributed throughout the nervous system. Astrocytes are not only involved in the regulation of synaptic transmission, maintenance of extracellular homeostasis in the brain, control of blood-brain barrier permeability, and neuroprotection, but also regulate neuroinflammatory responses by differentiating into different phenotypes, such as pro- and anti-inflammatory astrocytes.
Due to the important roles of astrocytes in the regulation of central nervous system, the study of astrocyte function and polarization is becoming an important tool in the study of neurodegenerative diseases, such as frontotemporal dementia, Parkinson's and Alzheimer's, as well as neuroinflammatory diseases. Creative Biolabs has years of experience in the field of life science, focusing on customized services for astrocyte-associated mechanism of action studies, targeting profiling and drug screening for the development of novel therapies treating neurological diseases, and accelerating your drug discovery programs. We offer a variety of astrocyte assays, including monocultures, co-cultures, and ex vivo brain slice assays, to help you study the polarization and function of astrocytes in both neurodegenerative diseases and neuroinflammatory disorders, which enable you to discover the interactions of astrocytes with distinct compound candidates. Our neuroscientists are ready to design customized astrocyte assays for your drug discovery program and answer any questions you may have about your astrocyte assays.
Astrocyte Assay Services at Creative Biolabs
Creative Biolabs provides reliable in vitro astrocyte assays for our global customers. We use stable human induced pluripotent stem cell (hiPSC)-derived astrocytes for the in vitro assays, offering high-quality imaging for the observation of morphological differences in mature iPSC-derived astrocytes stained with specific markers, which enables a better understanding of astrocyte polarization. In addition, Creative Biolabs provides our clients with customized in vitro astrocyte phagocytosis assay for pathological mechanism research and development demands, exploration of the compound effects on astrocyte phagocytosis, and drug candidate screening. To further understand neurofunctions and pro- or anti-inflammation responses of astrocytes, we provide unique monocultures, co-cultures, and ex vivo brain slice assays.
For a better investigation of astrocytes, Creative Biolabs offers a comprehensive in vitro astrocyte assay service for researchers worldwide. You can thus find a more convenient, efficient, professional, reliable, and customized approach to your drug candidates for neuropathologies, which is the key to delivering therapies to the market. Our expert scientists are willing to guide you in answering questions around astrocyte polarization and function. We guarantee low-risk and high-quality assays to accelerate your research for both neurodegenerative diseases and neuroinflammation. For further information, please feel free to contact us.