NeuroMab™ Anti-Sortilin BBB Shuttle Antibody(NRZP-1022-ZP2770)
[CAT#: NRZP-1022-ZP2770]
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mammalian
- Applications:
- ELISA; Inhib; In Vitro; In Vivo; Antagonist
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human; Mammalian
Clonality
Monoclonal
Host Species
Mouse
Applications
ELISA; Inhib; In Vitro; In Vivo; Antagonist
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
SORT1
Official Name
SORT1
Full Name
Sortilin
Alternative Names
SORT1; Gp95; LDLCQ6; NT3; NTR3; Sortilin 1
Product Pictures
Inhib
Figure 2 shows flow cytometric analysis of human PBMCs stained with Fab variants "muCD45R0" and "huCD45R0_v1".
Inhib
Figure 3 shows flow cytometry analysis of human PBMCs stained with Fabs against CD45R0.
Inhib
Figure 4 shows the flow cytometric analysis of human T cells stained with the Fab variants "muCD45R0" and "huCD45R0_v3".
WB
Figure 1 shows murine MMP-12 activity (Fluo/sec) in the presence of increasing concentrations (nM) of MMP-12 binding protein (539B-M11H11 IgG).
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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