Name: iNeuMab™ Anti-Kv8.2 potassium channel BBB Shuttle Antibody (NRZP-0423-ZP234)
SKU: NRZP-0423-ZP234
Rating: 5 (1 reviews)

Product Overview

Description

The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-KCNV2 BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.

Immunogen

Fusion protein amino acids 1-163 (cytoplasmic N-terminus) of mouse Kv8.2 (also known as Potassium voltage-gated channel subfamily V member 2, Kcnv2 and rCG_63626, accession number Q8CFS6)
Rat: 85% identity (138/163 amino acids identical)
Human: 70% identity (115/164 amino acids identical)

Construction

We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.

Species Reactivity

Mouse

Clonality

Monoclonal

Isotype

IgG2b

Research Areas

K+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

KCNV2

Official Name

KCNV2

Full Name

Kv8.2 K+ channel

Alternative Names

Potassium Voltage-Gated Channel Modifier Subfamily V Member 2; Potassium Channel; Voltage Gated Modifier Subfamily V; Member 2; Voltage-Gated Potassium Channel Subunit Kv8.2; Potassium Channel; Subfamily V; Member 2; Potassium Voltage-Gated Channel Subfamily V Member 2; Kv11.1; Kv8.2; RCD3B;