iNeuMab™ Anti-Tau Antibody (NRP-0422-P2275)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
NRP-0422-P2275 is an IgM-class monoclonal antibody that stains the fibrillar pathology (dystrophic neurites, neurofibrillary tangles, and neuropil threads) commonly observed in postmortem histological analysis of Alzheimer's disease (AD)1 brain. NRP-0422-P2275 reacts with tau and that its epitope is located at the N terminus (11-13) of human tau.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgM
Applications
WB; ELISA; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
>95% by SDS PAGE or HPLC
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Target
Tau
Official Name
Tau
Alternative Names
MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Publications
Publications (0)
Neural Antibodies
Kits
Neural Genes
Scientific Resources
Customer Reviews and Q&As
Customer Reviews
Average Customer Ratings
Overall
5.0
ExcellentA must-have for tauopathy researchIt has provided us with consistent results in both Western blotting and immunofluorescence assays. The antibody's high specificity minimizes background noise, enhancing our data clarity.
ExcellentThe results have been consistent and reliableWe switched to the antibody, after experiencing issues with other antibodies. The difference was remarkable. The antibody's performance in our ELISA assays has been outstanding, giving us reliable and reproducible data.
ExcellentIt's definitely worth the investmentThe high specificity and low background staining of the antibody, make it an excellent choice for immunohistochemistry. It has significantly improved the quality of our staining, making it easier to interpret our results.
ExcellentHighly recommendedAfter trying multiple tau antibodies, we found the NeuroMab™ Anti-Tau Antibody, Clone NR2218P, to be the most reliable. Its high specificity and sensitivity have made a significant difference in our research on neurodegenerative diseases.
ExcellentThe antibody's high specificity is particularly noteworthyThe performance of the antibody in our experiments has been exceptional. The antibody's ability to detect tau protein with high specificity has greatly enhanced our research on tauopathies. It's a top-notch product.
Q&As
What are the recommended dilution ratios for different applications?
For Western blotting, a typical dilution range of 1:1000 to 1:2000 is recommended. For immunohistochemistry and immunofluorescence, a dilution of 1:200 to 1:500 is suggested, depending on the tissue type and antigen retrieval methods used. It is advisable to optimize the dilution for your specific experimental conditions for best results.
Can this antibody be used for detecting phosphorylated Tau?
Although the antibody primarily targets non-phosphorylated Tau, it does recognize certain phosphorylated forms. However, for specific studies focusing exclusively on phosphorylated Tau, using an antibody specifically designed for phosphorylated epitopes may provide more accurate results. It’s crucial to review experimental requirements before selection.
Are there any known non-specific bindings or cross-reactivities associated with this antibody?
The antibody has been rigorously tested for specificity and is known to have minimal non-specific bindings or cross-reactivities. However, as with any antibody, it is essential to include appropriate controls in your experiments to ensure the validity of your results. Testing in your specific experimental conditions is recommended.
What support is available if I encounter issues with the antibody in my experiments?
If you encounter any issues with the antibody, our technical support team is readily available to assist you. We offer comprehensive troubleshooting guides, detailed product datasheets, and personalized support to help you optimize your experiments and resolve any challenges. Our goal is to ensure that you achieve the best possible results with our antibody.
For Research Use Only. Not For Clinical Use.
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