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Creative Biolabs

NeuroMab™ Anti-Amyloid Beta 1-42 BBB Shuttle Antibody(NRZP-1022-ZP3518)

[CAT#: NRZP-1022-ZP3518]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; ELISA; FC; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Immunogen

hNav1.7-loopA3

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; ELISA; FC; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

AmyloidBeta1-42

Official Name

Amyloid Beta

Full Name

Amyloid Beta

Alternative Names

APP; Aβ; Abeta; Amyloid β
Product Pictures
ELISA

Figure 1. Shows the binding affinity of Nav1.7 antibodies raised by peptide immunization to human Nav1.7 extracellular loop A3 measured by ELISA.

Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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