NeuroMab™ Anti-CX3CR1 BBB Shuttle Antibody(NRZP-1022-ZP3788)
[CAT#: NRZP-1022-ZP3788]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- Cyt; Neut; In Vitro; In Vivo
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Applications
Cyt; Neut; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease; Parkinson's Disease; Neuroinflammation
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
CX3CR1
Official Name
CX3CR1
Full Name
C-X3-C Motif Chemokine Receptor 1
Alternative Names
GPR13; CMKBRL1
Product Pictures
FuncS
Figure 1A shows the effect of anti-fractalkine (FKN) monoclonal antibody on ConA-induced hepatitis in mice.
FuncS
Figure 1B shows the effect of anti-fractalkine (FKN) monoclonal antibody on ConA-induced hepatitis in mice.
FuncS
Figure 1C shows the effect of anti-fractalkine (FKN) monoclonal antibody on ConA-induced hepatitis in mice.
FuncS
Figure 2A shows the effect of anti-fractalkine (FKN) antibody on cytokine increase 2 hours after ConA injection.
FuncS
Figure 2B shows the effect of anti-fractalkine (FKN) antibody on cytokine increase 2 hours after ConA injection.
FuncS
Figure 3 shows the effect of anti-fractalkine (FKN) antibody on experimental autoimmune encephalomyelitis.
Cyt
Figure 4 shows the cytotoxicity of saporin-labeled anti-CX3CR1 antibody on CX3CR1-expressing cells.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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