Mouse Anti-CX3CR1 Monoclonal Antibody (CBP2869)
[CAT#: NAB20101947CR]
Mouse Monoclonal (3D3B8) to CX3CR1
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; ELISA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
CX3CR1 belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).
Expression Host
Mammalian cells
Immunogen
CX3CR1 fusion protein Ag27698
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2869
Applications
WB; ELISA
Application Notes
WB : 1:500-1:1000
Research Areas
Growth and Development
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
CX3CR1
Official Name
CX3CR1
Full Name
Chemokine (C-X3-C motif) receptor 1
Alternative Names
Beta chemokine receptor like 1; C X3 C CKR 1; CCRL1; CMK BRL 1; CMK BRL1; CMKBRL1; CMKDR1; CX3C chemokine
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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