NeuroMab™ Anti-IL-6 Antibody(NRP-0422-P1515)
Functional antibody against Human IL-6
- Host Species:
- Humanized
- Species Reactivity:
- Human
- Applications:
- Inhib; Block; In Vitro; In Vivo; Neut
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Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Isotype
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 shows the inhibition of T1165 cell proliferation induced by human recombinant, human mammalian, rhesus monkey, rhesus monkey and mouse IL-6 by antibody 240.g1.
Figure 2 shows the inhibition of MCP-1 production induced by human recombinant IL-6 and sIL-6R in HUVECs by antibody 240.g1.
Figure 3 shows the inhibition of IL-17-induced endogenous IL-6 and sIL-6R-induced MCP-1 production in HU VECs by antibody 240.g1.
Figure 4 Neutralization of hIL-6-induced SAA in mice by administration of CA030_240.g1 (site 3 antibody) n=7-8/group except PBS n=6. **P<0.01 compared with IL-6 alone, statistical analysis by ANOVA with Bonferroni post hoc test.
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