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Creative Biolabs

NeuroMab™ Anti-Tau Antibody(NRP-0422-P1668)

[CAT#: NRP-0422-P1668] Review(5) Q&As(3)

Functional antibody against Human Tau

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; ELISA; ICC; IHC

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Product Overview

Description

NRP-0422-P1668 antibody recognizes all tau isoforms. NR2264P produces abundant staining of NFT, dystrophic neurites in plaques, and dispersed staining of neuropil (neuropil threads). The monoclonal antibodies can be used to detect tau and abnormally phosphorylated tau in brain extracts and in unconcentrated cerebrospinal fluid.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Applications

WB; ELISA; ICC; IHC

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Tau

Official Name

Tau

Full Name

Tau

Alternative Names

CD14

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
Overall, a highly reliable antibody for neurodegenerative research
We primarily use it for Western Blotting, and it consistently provides clear, specific bands with minimal background noise. The antibody's sensitivity is impressive, allowing us to detect even low levels of tau protein.
user
Excellent
I have used the antibody for Western Blot and ICC applications
The antibody provides excellent specificity and clarity in WB, producing distinct bands that are easy to interpret. For ICC, the antibody beautifully stains tau in cultured neurons, highlighting fine structural details without excessive background.
user
Excellent
It provides strong, specific signals that are easy to quantify
The antibody's robustness and reproducibility have significantly enhanced the quality of our data. Additionally, the customer support from Creative Biolabs has been exceptional, assisting us in troubleshooting and optimizing our protocols.
user
Excellent
One of the best antibodies for detecting tau protein
The antibody provides clear and specific staining of tau protein in cultured neurons, highlighting intricate cellular structures. Its high specificity ensures that our observations are accurate and reliable.
user
Excellent
A high-quality antibody that we highly recommend
We've been using the antibody in our Alzheimer's research, and it has proven to be an excellent choice. The antibody provides strong, specific signals in Western Blot and ELISA, allowing us to accurately measure tau levels.
Q&As
How specific is the antibody to different tau isoforms or phosphorylated states?
The Clone NR2264P is meticulously validated for its specificity to tau protein across its various isoforms. It recognizes both phosphorylated and non-phosphorylated forms, which is crucial for differentiating between normal tau function and pathological states. This antibody has undergone extensive testing to ensure minimal cross-reactivity with other proteins, making it an excellent tool for detailed tau analysis in your research.
Are there any published studies that have used this antibody, and can you provide examples?
Yes, numerous studies have utilized the antibody. For example, it has been employed in research examining tau pathology in Alzheimer's disease models, contributing to insights into disease mechanisms. Peer-reviewed articles often cite its use in characterizing tau distribution in brain tissues. For specific references, we recommend checking our website or contacting our support team for a list of relevant publications.
What is the delivery time for this antibody, and do you offer any customer support for experimental troubleshooting?
Typically, the antibody is shipped within 1-2 weeks after order placement, depending on stock availability. We prioritize efficient delivery to support your research timelines. Additionally, our customer support team is available to assist with any experimental troubleshooting or technical queries you may have. We provide comprehensive support to ensure your experiments with our products are successful and productive.
For Research Use Only. Not For Clinical Use.
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