iNeuMab™ Anti-Siglec-7 BBB Shuttle Antibody (NRZP-1022-ZP2653)

Name: iNeuMab™ Anti-Siglec-7 BBB Shuttle Antibody (NRZP-1022-ZP2653)
SKU: NRZP-1022-ZP2653
Rating: 5 (1 reviews)

[CAT#: NRZP-1022-ZP2653]

Host Species:: Mouse; Humanized

Species Reactivity:: Human; Cynomolgus Monkey; Mouse

Applications:: FC; ELISA; Block; In Vitro; In Vivo; Antagonist

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human; Cynomolgus Monkey; Mouse

Clonality

Monoclonal

Host Species

Mouse; Humanized

Applications

FC; ELISA; Block; In Vitro; In Vivo; Antagonist

Relevant Diseases

Alzheimer's Disease; Multiple Sclerosis

Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only

Target

Siglec7

Official Name

SIGLEC7

Full Name

Sialic Acid Binding Ig Like Lectin 7

Alternative Names

Sialic Acid Binding Ig Like Lectin 7; QA79 Membrane Protein; SIGLEC-7; D-Siglec; AIRM-1; CDw328; AIRM1; P75; Sialic Acid Binding Ig-Like Lectin 19; Pseudogene; Adhesion Inhibitory Receptor Molecule 1; Siglec-7; Sialic Acid Binding Ig-Like Lectin; Pseudogene 2;

Publications