NeuroMab™ Anti-Brevican BBB Shuttle Antibody, Clone N294A/6
[CAT#: NRZP-0423-ZP51]
- Species Reactivity:
- Rat; Mouse
- Applications:
- WB; IHC; ICC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
The BBB is a highly selective membrane that surrounds the blood vessels in the brain, and it can prevent many molecules, including potentially life-saving drugs, from entering the brain. The anti-Brevican BBB Shuttle Antibody is designed to bind to receptors on the surface of cells in the BBB, and once bound, the antibody can cross the BBB and into the brain. This technology has the potential to revolutionize the treatment of brain disorders by enabling drugs to reach the brain more effectively.
Immunogen
Fusion protein amino acids 219-655 of rat Brevican (also known as Brevican core protein, Brainenriched hyaluronan-binding protein, BEHAB, BCAN, Chondroitin sulfate proteoglycan 7 and CSPG7, accession number P55068)
Mouse: 92% identity (403/437 amino acids identical)
Human: 75% identity (350/464 amino acids identical)
<40% identity with Aggrecan
Mouse: 92% identity (403/437 amino acids identical)
Human: 75% identity (350/464 amino acids identical)
<40% identity with Aggrecan
Construction
We offer several options for BBB shuttle antibody design. Antibody construction can be customized according to customer requirements.
Species Reactivity
Rat; Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
N294A/6
Applications
WB; IHC; ICC
Research Areas
Scaffolds
Conjugation
Unconjugated
Product Properties
Research Use Only
For reseaech use only, not for human or dignostic use.
Target
Target
Brevican
Official Name
BCAN
Full Name
Brevican
Alternative Names
BCAN; BEHAB; CSPG7; Brevican
Uniprot ID
P55068
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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