NeuroMab™ Anti-CXCR4 BBB Shuttle Antibody(NRZP-1022-ZP3815)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- Inhib; In Vitro
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1 is a graph showing that single chain antibodies Ab124 and Ab125 can inhibit SDF-1-induced chemotaxis in the human breast cancer cell line MDA-MB-231.
Figure 2 is a graph showing that both scFvs directed against human CCR5 Loop 6 are able to block the binding of MIP-la to CCR5 on human monocyte-derived macrophages.
Figure 3 shows a Western blot of human CCR5 loop 6 of human macrophage-expressed CCR5 probed with scFv.
Figure 4A shows HIV-1 reverse transcriptase (RT) activity in HIV-1 infected human monocyte cultures in the presence or absence of antibodies at days 4, 8 and 12 post infection, respectively.
Figure 4B shows HIV-1 reverse transcriptase (RT) activity in cultures of human monocytes infected with HIV-1 in the presence or absence of antibodies at days 4, 8 and 12 post-infection, respectively.
Figure 4C shows HIV-1 reverse transcriptase (RT) activity in human monocyte cultures infected with HIV-1 in the presence or absence of antibodies at days 4, 8 and 12 post-infection, respectively.
Figure 5A shows the viability of human monocyte cultures infected with HIV-1 in the presence or absence of antibodies on days 4, 8 and 12 post-infection, respectively.
Figure 5B shows the viability of human monocyte cultures infected with HIV-1 in the presence or absence of antibodies on days 4, 8 and 12 post-infection, respectively.
Figure 5C shows the viability of human monocyte cultures infected with HIV-1 in the presence or absence of antibodies on days 4, 8 and 12 post-infection, respectively.
Figure 6A shows HIV-1 reverse transcriptase (RT) activity in cultures of human monocytes infected with HIV-1 in the presence or absence of antibodies at days 4, 8 and 12 post-infection, respectively.
Figure 6B shows HIV-1 reverse transcriptase (RT) activity in human monocyte cultures infected with HIV-1 in the presence or absence of antibodies at days 4, 8 and 12 post-infection, respectively.
Figure 6C shows HIV-1 reverse transcriptase (RT) activity in human monocyte cultures infected with HIV-1 in the presence or absence of antibodies at days 4, 8 and 12 post-infection, respectively.
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