NeuroMab™ Anti-ABCG2 Antibody(NRZP-1222-ZP858)

Product Overview

Description

ABCG2 is an ATP-binding cassette (ABC) transporter whose function affects the pharmacokinetics of drugs and contributes to multidrug resistance of cancer cells. Fab fragments of the ABCG2-specific monoclonal antibody 5D3 binds to the external side of the transporter but does not interfere with drug-induced stimulation of ATPase activity.

Species Reactivity

Human

Host Species

Mouse

Applications

In Vitro

Relevant Diseases

Alzheimer's Disease

Target

ABCG2

Official Name

ABCG2

Full Name

ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group)

Alternative Names

ATP Binding Cassette Subfamily G Member 2 (Junior Blood Group); ATP-Binding Cassette; Sub-Family G (WHITE); Member 2 (Junior Blood Group); Placenta-Specific ATP-Binding Cassette Transporter; Mitoxantrone Resistance-Associated Protein; Breast Cancer Resistance Protein; Urate Exporter; CDw338; BCRP1; ABCP; BCRP; MXR; Multi Drug Resistance Efflux Transport ATP-Binding Cassette Sub-Family G (WHITE) Member 2; ATP-Binding Cassette; Sub-Family G (WHITE); Member 2; ATP-Binding Cassette Sub-Family G Member 2;

Publications