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Creative Biolabs

NeuroMab™ Anti-c-kit BBB Shuttle Antibody(NRZP-1222-ZP999)

[CAT#: NRZP-1222-ZP999]

Host Species:
Human
Species Reactivity:
Human
Applications:
Antagonist; In Vitro; Block

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Product Overview

Description

The overexpression and activation of c-kit are thought to promote tumor growth and have been reported in various cancers. The c-kit antagonist human antibody binds to domain 2/3 of c-kit. This completely blocked the SCF-mediated phosphorylation of c-kit and inhibited TF-1 cell proliferation, erythroleukemia.

Species Reactivity

Human

Host Species

Human

Applications

Antagonist; In Vitro; Block

Relevant Diseases

Tumor
Target

Target

c-kit

Official Name

KIT

Full Name

Proto-oncogene c-KIT
Publications

Publications (0)

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